2 hydroxy p naphthoquinone

2 hydroxy p naphthoquinone

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2 hydroxy p naphthoquinone

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A hydroxynaphthoquinone formula: C 10 H 6 O 3 is any of several organic compounds that can be viewed as derivatives of a naphthoquinone through replacement of one hydrogen atom H by a hydroxyl group -OH. In this case the number n which is between 1 and 6 is indicated by a multiplier prefix mono -, di -, tri -, tetra -, penta -, or hexa -. The unqualified term "hydroxynaphthoquinone" usually means a derivative of 1,4-naphthoquinone. Other hydroxy- compounds can be derived from other isomers of the latter, such as 1,2-naphthoquinone and 2,6-naphthoquinone. The hydroxynaphtoquinones in the particular or the general sense include many biologically and industrially important compounds, and are a building-block of many medicinal drugs.

2 hydroxy p naphthoquinone

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. The treatment of Staphylococcus aureus S. Here, we report the synthesis of a lawsone 2-hydroxy-1,4-naphthoquinone -based compound as an antimicrobial agent against methicillin-resistant S. A series of lawsone-derivative compounds were synthesized by means of tuning the lipophilicity of lawsone and screened for minimum inhibitory concentrations against MRSA to identify a candidate compound that possesses a potent antibacterial activity. The identified lawsone-derivative compound exhibited significantly improved drug resistance profiles against MRSA compared to conventional antibiotics. The therapeutic efficacy of the compound was validated using murine models of wound infection as well as non-lethal systemic infection induced by MRSA. Our study further revealed the multifaceted modes of action of the compound, mediated by three distinctive mechanisms: 1 cell membrane damage, 2 chelation of intracellular iron ions, and 3 generation of intracellular reactive oxygen species.

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Cryogenic Storage. Other solubilities: soluble in benzene,carbon tetrachloride,aceton,,petroleum ether and sodium hydroxide Formula Weight Here you can modify parameters that will directly affect your browsing experience on this website. See All Categories. Estimated delivery in Latvia, on Monday 25 Mar Add to cart. This item is not returnable. Cookies are important for you, they influence your browsing experience, they help us to protect your privacy and allow us to proceed with the requests that you demand through this website. Syringes and Needles. Found 14 products. Cell Culture Media. Ref: 1g Estimated delivery in Latvia, on Friday 15 Mar This search does not contain any category.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. Harmful if swallowed.

Analytic and Marketing Cookies They allow anonymous measurement of the number of visits or the activity. Use Analytic and Marketing cookies unselected means that we will not be able to offer you a continuous improvement in your browsing experience. Estimated delivery in Latvia, on Monday 18 Mar They help us to tailor your browsing experience. Estimated delivery in Latvia, on Thursday 2 May Recombinant Proteins Recombinant Proteins. No offer available. Ref: 3B-H 25g Custom Assays, Antibodies, Oligos. Calibration Weights. Estimated delivery in Latvia, on Friday 22 Mar Add to cart. Estimated delivery in Latvia, on Monday 25 Mar Flow Cytometry.

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