Milk thistle zararları

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How to use: For adults, it is recommended to take 1 capsule 2 times a day after meals and dissolve 1 sachet in a glass ml of water once a day and take after meals. Recommended consumption date and lot number are on the packaging. Store at room temperature, protect from heat and light. Additional Information: Do not exceed the recommended daily dose. Supplements cannot replace a normal diet. Keep out of reach of children. It is not a medicine.

Milk thistle zararları

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Keep out of reach of children.

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Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Other benefits include promoting healthy digestive function, increasing bile production , decreasing inflammation and soothing the mucous membranes throughout the body. The milk thistle plant is a popular herb that has actually been used for over 2, years. The plant is native to the Mediterranean region and a member of the Asteraceae plant family, which also includes other plants like sunflowers and daisies. Milk thistle is commonly used for everything from weight loss to skin health to promoting breast milk production.

Milk thistle zararları

Milk thistle Silybum marianum is a herb loaded with antioxidants and is known for its anti-inflammatory properties. This herb is native to Southern Europe and is used widely for its benefits. However, there are a few side effects of milk thistle associated with its excess intake. Allergic reactions, abdominal problems, and estrogen and drug interactions are some of the common side effects seen in people who take this herb for extended durations. Learn more about the other negative effects of this herb and what research says about them. Continue reading. Long-Term Effects May aggravate conditions like endometriosis, and lower blood sugar levels too much. Drug Interactions It can interact with drugs like estrogen pills, statin drugs, which are known to lower cholesterol levels, and diabetes medications.

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Food Supplement Approval Number: An updated systematic review of the pharmacology of silymarin. Manuscript under submission.. Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs. This protection can be related to its antioxidant and free radical scavenging actions. Effects of silymarin or silybinin on breast cancer 27 - 28 , ovarian cancer, lung cancer 29 , skin cancer 30 , prostate cancer 31 - 33 , cervical cancer, bladder cancer, liver carcinoma 34 , and colon cancer 35 , have been reported 6. Luorno, et al. It has been also illustrated that silymarin is not teratogen and had no post-mortem toxicity 2 , 5 , Carcinoma Clin Cancer Res. Cambridge University Press, pp. Silybin and silymarin - New and emerging applications in medicine. Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: involvement of maintenance of Akt kinase activation. It stimulates T-cell transcription factor and plays an important role in regulation of oncogenic process, as well as anti-apoptotic effects in various cancers. Clinical Epidemiology 6 In non-alcoholic fatty liver disease NAFLD , elevation of circulating free fatty acids and their levels correlate with disease severity.

One of the active ingredients in milk thistle called silymarin is extracted from the plant's seeds. Silymarin is believed to have antioxidant properties. Milk thistle is sold as an oral capsule, tablet and liquid extract.

Milk thistle , a member of Carduus marianum family, is an ancient medicinal plant which has been used for centuries for treatment of different diseases such as liver and gallbladder disorders, protecting liver against snake bite and insect stings, mushroom poisoning and alcohol abuse 1. Estrogenic effects of silymarin lead to increasing the uterine weight and endometrial height, in addition to hypertrophy of luminal epithelium. A primary role for MRP2, a cell membrane transporter, has been showed in the biliary excretion of silymarin conjugates. Reactive oxygen species and reactive nitrogen species: relevance to cyto neuro toxicity events and neurological disorders. Milk thistle was first grown in Europe and used as a liver tonic as it was said to be able to open the obstructions of the liver and spleen, and thereby was good for jaundice Nicolas Culpepper, 3. Front Pharmacol. Thus, liver diseases remain one of the serious health problems. Toxicol Appl Pharmacol. This protection can be related to its antioxidant and free radical scavenging actions. Dupont, et al. Silymarin and epithelial cancer chemoprevention: How close we are to bedside? Metodiewa D, Koska C. These protective effects have been illustrated in the fields of nephrotoxicity, hepatotoxicity, viral hepatitis, cancer, in vitro fertilization, neurotoxicity, depression, lung diseases, prostate diseases etc. Inhibitory effect of TNF-, on erythropoiesis and suppression of bone marrow via prevention of producing the erythroid colony forming units E-CFU , an early development precursor of red cells, causes problems in hematological status in advanced renal failure patients. Silymarin was administrated 20 days after 9 weeks treatment with alloxan and it was effective on the renal tissue injuries.