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Mirna silva

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Includes Address 10 Phone 2 Email 1. Disclaimer: By using this website, you accept the Spokeo Terms of Use. Lived In Philadelphia PA, mirna silva.

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Breast cancer is the most common cancer in women. The main organs in which BC metastasises are the bones, lungs, liver, and brain. Researchers are therefore seeking biomarkers for diagnosis and metastasis in different organs. Optimally, such biomarkers should be easy to detect using, preferably, non-invasive methods, such as using miRNA molecules, which are small molecules of about 22 nt that have as their main function the post-transcriptional regulation of genes. Furthermore, due to their uncomplicated detection and reproducibility in the laboratory, they are a tool of complementary interest for diagnosis, prognosis, and treatment. With this in mind, in this review, we focus on describing the most current studies that propose using miRNA independently as a potential biomarker for the diagnosis and prediction of brain, lung, liver, and bone metastases, as well as to open a window of opportunity to deepen this area of study to eventually use miRNAs molecules in clinical practice for the benefit of BC patients. Keywords: breast cancer subtypes; diagnostic; metastasis; microRNA.

Mirna silva

Federal government websites often end in. The site is secure. Individual raw data is available from the corresponding author upon reasonable request. In this study we compared six commercial RNA extraction kits to evaluate their ability to isolate miRNA from ovine plasma. We also compared three methods for quantification of small RNA extracted from plasma to determine the most reliable. Using minimal sample inputs of fresh and frozen plasma from five sheep, we compared the six kits Kit A-F using quantitative PCR.

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