Ondansetron moa

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Ondansetron moa

Official websites use. Share sensitive information only on official, secure websites. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT 3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Ondansetron comes as a tablet, a rapidly disintegrating dissolving tablet, film, and an oral solution liquid to take by mouth. The first dose of ondansetron is usually taken 30 minutes before the start of chemotherapy, 1 to 2 hours before the start of radiation therapy, or 1 hour before surgery. Additional doses are sometimes taken one to three times a day during chemotherapy or radiation therapy and for 1 to 2 days after the end of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ondansetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking the rapidly disintegrating tablet, remove the tablet from the package just before you take your dose. To open the package, do not try to push the tablet through the foil backing of the blister.

Using ondansetron during cesarean section does not affect the onset of breastfeeding.

Ondansetron , sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy , radiation therapy , or surgery. Common side effects include diarrhea , constipation , headache , sleepiness , and itchiness. Ondansetron was patented in and approved for medical use in Ondansetron is indicated for the prevention of chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting. Ondansetron is used off-label to treat morning sickness and hyperemesis gravidarum of pregnancy. It is typically used after other antinausea drugs have failed. A large multi-center cohort study found no association between ondansetron exposure and fetal risk compared to other antiemetic drugs.

Federal government websites often end in. The site is secure. Its use under these circumstances is both prophylactic and therapeutic. It has a superior efficacy, safety and pharmacoeconomic profile compared with other groups of antiemetics, namely antidopaminergics, antihistamines and anticholinergics. However, its place in the management of anticipatory and delayed vomiting in cancer treatment and as a rescue antiemetic in surgical patients needs to be further explored. Furthermore, recent animal and human research also reflects its possible novel application in the treatment of other disease states, such as alcoholism, cocaine addiction, opioid withdrawal syndrome, anxiety disorders, gastrointestinal motility disorders, Tourette's syndrome and pruritus. These references are in PubMed.

Ondansetron moa

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NCBI Bookshelf. Retrieved 4 November Archived from the original on 14 December The lower bioavailability is attributed to first-pass metabolism. Choose 3. Retrieved 5 March Consequently, ondansetron should be used with caution, and the maximum recommended daily intravenous dose isis reduced to 8 mg. Browse Drugs and Medicines. Are you sure you want to trigger topic in your Anconeus AI algorithm? Electrolyte imbalances should be corrected before the use of injectable ondansetron. Choose 2. Before taking ondansetron, tell your doctor and pharmacist if you are allergic to ondansetron, alosetron Lotronex , dolasetron Anzemet , granisetron Kytril , palonosetron Aloxi, in Akynzeo , any other medications, or any of the ingredients in ondansetron products. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at

Nausea and vomiting are common complaints seen by emergency department physicians and primary care clinicians daily.

Evidence Evidence. Routes of administration include oral, intramuscular IM , and intravenous IV. In: StatPearls [Internet]. Health Canada. S2CID Do not chew the film. Follow NCBI. An antidote to ondansetron is not known. Article Talk. Ask your pharmacist any questions you have about refilling your prescription. J Pediatr Gastroenterol Nutr.