Oxu

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Our high-value, near-term pipeline uses our innovative technology to create differentiated product candidates with the potential to transform the treatment paradigm for retinal disorders. OXU is being developed to provide retinal specialists with a potent, long-lasting, safe, and broad-acting anti-edema and anti-inflammatory for the treatment of DME, RVO and uveitis. Given this product profile, there is potential to expand OXU development to radiation maculopathy and specifically to radiation-induced macular edema. OXU are dexamethasone-containing Oxuspheres that are designed to be delivered via Oxulumis to the posterior suprachoroidal space as a highly efficacious, well-tolerated and durable treatment. DME patients are likely to have several underlying health issues and are often managed by multiple healthcare professionals. The burden of medical visits for these patients, who are typically of working age, frequently results in missed treatments and suboptimal treatment outcomes.

Oxu

OXU contains a proprietary narrow spectrum kinase inhibitor with potent anti-angiogenic and anti-inflammatory properties. OXU will be prepared using long-lasting Oxuspheres and is designed to be delivered via Oxulumis to the posterior suprachoroidal space. Preclinical studies with OXU demonstrate encouraging efficacy compared to benchmark clinical molecules, with favorable toxicology data supporting human use. Diabetic retinopathy is a serious, highly prevalent retinal disorder associated with an increased risk of vision-threatening events like retinal neovascularization, bleeding, or retinal edema. Diabetic retinopathy affects approximately ninety-five million people globally, requiring, in more advanced stages, retinal laser therapy or frequent intravitreal injections and physician visits to prevent permanent vision loss or blindness. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. Close Privacy Overview This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent.

OXU is being developed to provide retinal specialists with a potent, long-lasting, safe, and broad-acting anti-edema and anti-inflammatory for the treatment oxu DME, RVO and uveitis. Create widget, oxu.

The IND enables advancement of the OXEYE Phase 2 trial, which will evaluate the safety and efficacy of OXU and the potential to provide retinal specialists with a potent, long-lasting, safe, and broad-acting anti-edema and anti-inflammatory treatment for high-prevalence retinal disorders, beginning with DME. This in-office treatment could lead to enhanced efficacy, favorable tolerability, and extended durability to address key unmet needs for people with DME and other retinal disorders. In month preclinical studies, OXU was well-tolerated and related pharmacokinetic data confirmed that therapeutic drug levels were consistently maintained in target retinal tissues. These data suggest that a single treatment of OXU may provide up to twelve-month treatment effects with an improved clinical safety profile. The opportunity to provide patients with a targeted, in-office treatment just once a year could be a game-changer for this prevalent disease. We look forward to advancing OXU into the clinic and evaluating its therapeutic impact in

Our high-value, near-term pipeline uses our innovative technology to create differentiated product candidates with the potential to transform the treatment paradigm for retinal disorders. OXU is being developed to provide retinal specialists with a potent, long-lasting, safe, and broad-acting anti-edema and anti-inflammatory for the treatment of DME, RVO and uveitis. Given this product profile, there is potential to expand OXU development to radiation maculopathy and specifically to radiation-induced macular edema. OXU are dexamethasone-containing Oxuspheres that are designed to be delivered via Oxulumis to the posterior suprachoroidal space as a highly efficacious, well-tolerated and durable treatment. DME patients are likely to have several underlying health issues and are often managed by multiple healthcare professionals. The burden of medical visits for these patients, who are typically of working age, frequently results in missed treatments and suboptimal treatment outcomes. OXU has the potential to address the significant unmet needs of these patients through i long treatment durability and significantly fewer injections; ii better efficacy through sustained treatment benefits; iii better safety through tissue-specific delivery and minimized off-target side effects; and iv routine administration through minimally invasive microcatheterization to the suprachoroidal space.

Oxu

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The company has engineered sustained-release drug formulations designed to last up to one year following single dosing and delivery technology to access tissues in the posterior suprachoroidal space via routine, in-office administration. The IND enables advancement of the OXEYE Phase 2 trial, which will evaluate the safety and efficacy of OXU and the potential to provide retinal specialists with a potent, long-lasting, safe, and broad-acting anti-edema and anti-inflammatory treatment for high-prevalence retinal disorders, beginning with DME. Loading reviews Subscribe to all the latest releases from Business Wire by registering your e-mail address below. See More Content. Throughout the study period, only low drug levels were observed in off-target tissues associated with steroid side effects, including the vitreous and lens. These cookies will be stored in your browser only with your consent. You can unsubscribe at any time. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. About This Game Minimalistic 3d puzzle with portals, cubes and lasers. You also have the option to opt-out of these cookies. These data suggest that a single treatment of OXU may provide up to twelve-month treatment effects with an improved clinical safety profile. In month GLP preclinical studies, OXU was well-tolerated, and related pharmacokinetic data confirmed that therapeutic drug levels were consistently maintained in target retinal tissues.

Currently, 6, students are studying at this higher educational institution, of these students are medical students.

The company has engineered sustained-release drug formulations designed to last up to one year following single dosing and delivery technology to access tissues in the posterior suprachoroidal space via routine, in-office administration. Back to top. All Languages Your Languages 54 Customize. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Change language. Sign In Sign in to add your own tags to this product. Click here to see them. All trademarks are property of their respective owners in the US and other countries. There are no more reviews that match the filters set above. Conventional waterborne silicone resins use emulsifiers. Scroll to Top. OXU will be prepared using long-lasting Oxuspheres and is designed to be delivered via Oxulumis to the posterior suprachoroidal space. We also use third-party cookies that help us analyze and understand how you use this website.