Propolis side effects diarrhea

Metrics details. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities.

Propolis is a mixture of pollen and beeswax collected by bees from certain plants and trees. Rich in flavonoids , a class of antioxidants, propolis has a long history of use as a natural treatment for many health problems, but more research is needed in humans to support its use. Although found in small quantities in honey, propolis is also widely available in supplement form. For example, propolis is used as an ingredient in certain products applied directly to the skin, such as ointments and creams. In addition, propolis is sometimes found in nasal sprays and throat sprays, as well as in mouthwash and toothpaste.

Propolis side effects diarrhea

Federal government websites often end in. The site is secure. There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, afflict a significant proportion of people throughout the world. The role of herbal-derived medicines has been extensively explored in order to develop new effective and safe strategies to improve the available gastrointestinal therapies that are currently used in the clinical practice. Studies on the efficacy of propolis a unique resinous aromatic substance produced by honeybees from different types of species of plants are promising and propolis has been effective in the treatment of several pathological conditions. This review, therefore, summarizes and critiques the contents of some relevant published scientific papers including those related to clinical trials in order to demonstrate the therapeutic value of propolis and its active compounds in the treatment and prevention of gastrointestinal diseases. Honey bees produce it by mixing their saliva and beeswax with the exudates obtained from plants like tree buds, sap flows, leaves, branches, and barks of plants found in the vicinity of the beehive. The ultimate goal of propolis is for bees to protect their hives by utilizing it to seal cracks and protect bees from predators and microorganisms and provide thermal insulation [ 1 — 3 ].

Zeitschrift fur Naturforschung C, J biosciences. The Journal of Supportive Oncology.

Federal government websites often end in. The site is secure. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities. In the digestive system, a protective effect of propolis on gastric ulcer has been reported, but a laxative effect has not yet been reported. We investigated the effect and the mechanism of action of water and ethanol extracts of Brazilian green propolis. We also investigated the effects of WEP on gastrointestinal transit and contractional tension of the ileum to uncover the mechanism of action of WEP. WEP treatment significantly restored stool frequency and stool weight in clonidine-induced constipation model mice, but not in loperamide-induced constipation model mice.

Federal government websites often end in. The site is secure. There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, afflict a significant proportion of people throughout the world. The role of herbal-derived medicines has been extensively explored in order to develop new effective and safe strategies to improve the available gastrointestinal therapies that are currently used in the clinical practice. Studies on the efficacy of propolis a unique resinous aromatic substance produced by honeybees from different types of species of plants are promising and propolis has been effective in the treatment of several pathological conditions. This review, therefore, summarizes and critiques the contents of some relevant published scientific papers including those related to clinical trials in order to demonstrate the therapeutic value of propolis and its active compounds in the treatment and prevention of gastrointestinal diseases.

Propolis side effects diarrhea

Federal government websites often end in. The site is secure. Propolis is a beekeeping product with a complex and highly variable chemical composition. Many beneficial health properties have been reported. In this review, we will be focusing on compiling the studies carried out with propolis on infectious diseases of greater medical relevance.

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Dou W. This is in addition to its potential to treat different forms of gastrointestinal cancer, as presented in this article. Effect of a novel type of propolis and its chemical fractions on glucosyltransferases and on growth and adherence of mutans streptococci. Asthma Cold and Flu Anxiety and Stress. Hunt R. Figure 1. Chemopreventive effects of silymarin against 1,2-dimethylhydrazine plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicity in the colon of gpt delta rats. Wirtz S. Ulcerative colitis UC , a subtype of inflammatory bowel disease, is a chronic inflammatory condition that causes a constant inflammation of the colonic mucosa. In general, compounds such as chlorogenic and ferulic acids can be detected in the water-soluble fraction of Brazilian green propolis, while compounds such as artepillin C 4-hydroxy-3,5-diprenylcinnamic acid , isosakuranetin, and drupanin 4-hydroxyprenylcinnamic acid can be detected in the ethanol-soluble fraction. Conclusions In conclusion, WEP treatment resulted in laxative effects in normal mice and clonidine-induced constipation mice, but did not induce diarrhea as an adverse side effect. The frequency and weight of stools from each mouse were measured at 2 h intervals for 6 h e.

Propolis is a resin-like material that bees produce from the sap of needle-leaved trees combined with their saliva and beeswax. Propolis is used as a sealant for bees to build their hives, but it may also be beneficial for humans.

For each mouse, GI transit was calculated as the percentage of the distance traveled by the charcoal relative to the whole length of the small intestine. Strong antihyperglycemic effects of water-soluble fraction of Brazilian propolis and its bioactive constituent, 3,4,5-tri-O-caffeoylquinic acid. Constipation is a symptom rather than a specific disease. In addition to the ability to induce UC, DSS is also used as a chemical agent to cause colon tumorigenesis, after a prior administration of carcinogenic initiators [ 68 , 69 ]. In that study, propolis treatment was effective in attenuating UC, by mechanisms associated with decrease in oxidative stress and inflammation, which are key parameters in the pathogenesis of the disease [ 56 ]. Clin Exp Pharmacol Physiol. Researchers attribute this to small sample sizes and how studies were organized and carried out. The frequency and weight of stools from each mouse were measured at 2 h intervals for 6 h e. But no mention by WebMD. Expert Review of Clinical Immunology. European Journal of Immunology.