Raphe

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These examples are programmatically compiled from various online sources to illustrate current usage of the word 'raphe. Send us feedback about these examples. Accessed 13 Mar. Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! See Definitions and Examples ». Log In. Examples of raphe in a Sentence.

Raphe

The dorsal raphe nucleus is one of the raphe nuclei. It is situated in the brainstem at the midline. It has rostral and caudal subdivisions:. The DRN issues serotonergic efferents to the hippocampal formation, limbic lobe, and amygdala these efferents are involved in regulation of memory processing. The dorsal raphe is the largest serotonergic nucleus and provides a substantial proportion of the serotonin innervation to the forebrain. Serotonergic neurons are found throughout the dorsal raphe nucleus and tend to be larger than other cells. A substantial population of cells synthesizing substance P are found in the rostral aspects, many of these co-express serotonin and substance P. There is also a population of catecholamine synthesizing neurons in the rostral dorsal raphe, and these cells appear to be relatively large. The dorsal raphe nucleus is rich in pre-synaptic serotonin 5-HT 1A autoreceptors , and it's believed that the action of the selective serotonin reuptake inhibitors SSRIs in this region is responsible for the latency of their antidepressant effect. The dorsal raphe nucleus has also been implicated in naloxone-induced morphine withdrawal. It is known that endogenous opioid receptors exist in the dorsal raphe nucleus, and that it is a focal point as an ascending and descending regulator. Pourshanazari et al. These are fascinating results; however no control was provided for the spread of electrical charge to other parts of the brain stem. It is quite possible that the charge spread to the nucleus raphes magnus and induced analgesia upon the rats. Knowing that the spread of charge across such a short area is very plausible, as is an alternate connection to the raphe magnus, these results could be called into question.

Kocsis, B. Neuroanatomy, Nucleus Raphe. The source data are provided as a Raphe Data file.

Add to word list Add to word list. Examples of raphe. In normal awake and slow wave sleep states, the raphe nucleus is releasing serotonin. From the Cambridge English Corpus. In the third group, with two valves, the raphes reached to the mid point of the conjoined leaflet. A raphe , or false commissure, was present in all 13 cases. The calcified raphe is seen in both views.

Its medial surface is covered by the mucous membrane of the mouth. Its lateral surface is separated from the ramus of the mandible by a quantity of adipose tissue. Its posterior border gives attachment to the Constrictor pharyngis superior; its anterior border, to part of the Buccinator. Underlying structures: There are no anatomical children for this anatomical part. IMAIOS and selected third parties, use cookies or similar technologies, in particular for audience measurement.

Raphe

The dorsal raphe nucleus is one of the raphe nuclei. It is situated in the brainstem at the midline. It has rostral and caudal subdivisions:. The DRN issues serotonergic efferents to the hippocampal formation, limbic lobe, and amygdala these efferents are involved in regulation of memory processing. The dorsal raphe is the largest serotonergic nucleus and provides a substantial proportion of the serotonin innervation to the forebrain. Serotonergic neurons are found throughout the dorsal raphe nucleus and tend to be larger than other cells. A substantial population of cells synthesizing substance P are found in the rostral aspects, many of these co-express serotonin and substance P. There is also a population of catecholamine synthesizing neurons in the rostral dorsal raphe, and these cells appear to be relatively large. The dorsal raphe nucleus is rich in pre-synaptic serotonin 5-HT 1A autoreceptors , and it's believed that the action of the selective serotonin reuptake inhibitors SSRIs in this region is responsible for the latency of their antidepressant effect. The dorsal raphe nucleus has also been implicated in naloxone-induced morphine withdrawal.

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Although not highly selective to serotonin neurons, pharmacological inactivation of the MRN induced conditioned place preference and ethanol reinstatement 29 , 30 , while electrical stimulation of the MRN suppresses lever pressing associated with reward The calcified raphe is seen in both views. Brainstem surgery remains challenging but can be a useful treatment strategy for lesions such as brainstem gliomas. Dolensek, N. The primate amygdala represents the positive and negative value of visual stimuli during learning. Consumption of the reward from only one of the two bottles triggered optogenetic stimulation Fig. Data were amplified using a MultiClamp B amplifier and stored on a computer using the pClamp10 software version These differences in physiology are often due to genetic polymorphisms, explaining increased susceptibility in patients with a family history of depression. Nature , — Franklin, K. The dorsal raphe: an important nucleus in pain modulation. Salas, R. Biol Psychiatry. Curzon, P.

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Pain Res Manag. Nutt, D. Processing reward and aversive information is essential for the survival of living organisms 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , These contradictory findings imply that serotonin neurons in the MRN might play an opposite role to the DRN in the processing of reward and aversive stimuli. English—Japanese Japanese—English. Neurons in monkey dorsal raphe nucleus code beginning and progress of step-by-step schedule, reward expectation, and amount of reward outcome in the reward schedule task. NCBI Bookshelf. The position of the bottle paired with light was counter-balanced between days 3 and 4. Front Aging Neurosci. Fiber photometry To record fluorescence signals, we used a custom-built fiber photometry system fabricated according to the previous reports 94 , 95 with minor changes. For histochemical analyses, similar results were obtained in at least 10 Supplementary Fig. Role of dorsal medial prefrontal cortex dopamine D1-family receptors in relapse to high-fat food seeking induced by the anxiogenic drug yohimbine. We also found that activation of MRN serotonin neurons reduced consummatory licking in the head-fixed setup and hedonic response in facial expression analysis, both of which are much less amenable to confounding memory function. Serotonin 5-HT 7 receptor in the ventral hippocampus modulates the retrieval of fear memory and stress-induced defecation. The post-test session was performed the day following the second conditioning session.