Watson 794 10mg
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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid becoming overheated or dehydrated during exercise and in hot weather. Dicyclomine can decrease your sweating, which can lead to heat stroke in a hot environment. Stop using dicyclomine and call your doctor right away if you have serious side effects such as confusion, hallucinations, unusual thoughts or behavior, fast or uneven heart rate, or if you urinate less than usual or not at all.
Watson 794 10mg
If you are a consumer or patient please visit this version. Dicyclomine hydrochloride is an antispasmodic and anticholinergic antimuscarinic agent. Dicyclomine hydrochloride occurs as a fine, white, crystalline, practically odorless powder with a bitter taste. It is soluble in water, freely soluble in alcohol and chloroform, and very slightly soluble in ether. Chemically, it is [Bicyclohexyl]carboxylic acid, 2- diethyl-amino ethyl ester, hydrochloride with the following structural formula:. Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract. Atropine did not affect responses to these two agonists. In vivo studies in cats and dogs showed dicyclomine to be equally potent against acetylcholine ACh - or barium chloride BaCI 2 - induced intestinal spasm while atropine was at least times more potent against effects of ACh than BaCI 2. In man, dicyclomine is rapidly absorbed after oral administration, reaching peak values within minutes. The principal route of elimination is via the urine Excretion also occurs in the feces, but to a lesser extent 8. Mean half-life of plasma elimination in one study was determined to be approximately 1. In subsequent studies, plasma concentrations were followed for up to 24 hours after a single dose, showing a secondary phase of elimination with a somewhat longer half-life. Mean volume of distribution for a 20 mg oral dose is approximately 3. In the presence of a high environmental temperature, heat prostration can occur with drug use fever and heat stroke due to decreased sweating.
CNS signs and symptoms include confusion, disorientation, short-term memory loss, hallucinations, dysarthria, ataxia, coma, euphoria, decreased anxiety, fatigue, insomnia, agitation and mannerisms, and watson 794 10mg affect. Effects of renal impairment on PK, safety and efficacy of dicyclomine hydrochloride has not been studied.
If you are a consumer or patient please visit this version. Dosage for dicyclomine hydrochloride must be adjusted to individual patient needs 2. If a dose is missed, patients should continue the normal dosing schedule 2. Oral in adults 2. The most serious adverse reactions include cardiovascular and central nervous system symptoms. After one week treatment with the initial dose, the dose may be increased to 40 mg four times a day unless side effects limit dosage escalation. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued.
Dicyclomine hydrochloride is an antispasmodic and anticholinergic antimuscarinic agent. Dicyclomine hydrochloride occurs as a fine, white, crystalline, practically odorless powder with a bitter taste. It is soluble in water, freely soluble in alcohol and chloroform, and very slightly soluble in ether. Chemically, it is [Bicyclohexyl]carboxylic acid, 2- diethyl-amino ethyl ester, hydrochloride with the following structural formula:. Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract. Atropine did not affect responses to these two agonists. In vivo studies in cats and dogs showed dicyclomine to be equally potent against acetylcholine ACh - or barium chloride BaCI 2 - induced intestinal spasm while atropine was at least times more potent against effects of ACh than BaCI 2. In man, dicyclomine is rapidly absorbed after oral administration, reaching peak values within minutes. The principal route of elimination is via the urine Excretion also occurs in the feces, but to a lesser extent 8.
Watson 794 10mg
After one week treatment with the initial dose, the dose may be increased to 40 mg four times a day unless side effects limit dosage escalation. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued. Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks.
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NDC National Drug Code - Each drug product is assigned this unique number which can be found on the drug's outer packaging. Sedatives e. In subsequent studies, plasma concentrations were followed for up to 24 hours after a single dose, showing a secondary phase of elimination with a somewhat longer half-life. This medication may impair your thinking or reactions. In the presence of a high environmental temperature, heat prostration can occur with drug use fever and heat stroke due to decreased sweating. Dicyclomine hydrochloride should be given to patients with myasthenia gravis only to reduce adverse muscarinic effects of an anticholinesterase 5. Take exactly as prescribed by your doctor. Manufactured by: Patheon Pharmaceuticals Inc. Advise lactating women that dicyclomine hydrochloride should not be used while breastfeeding their infants [see Use in Specific Populations 8. Mean volume of distribution for a 20 mg oral dose is approximately 3. Treatment should consist of gastric lavage, emetics, and activated charcoal. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued. Dialysis It is not known if dicyclomine is dialyzable. We recognize our responsibility and see it as an opportunity to improve lives and to make a lasting social impact.
If you are a consumer or patient please visit this version.
Some local irritation and focal coagulation necrosis may occur following the intramuscular injection of dicyclomine hydrochloride. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. Death has been reported. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. A curare-like action may occur i. Dosage must be adjusted to individual patient needs. The amount of drug in a single dose that is ordinarily associated with symptoms of overdosage or that is likely to be life-threatening, has not been defined. You should not take this medication if you are allergic to dicyclomine, or if you have: problems with urination; a bowel obstruction or severe constipation; severe ulcerative colitis or toxic megacolon; gastroesophageal reflux disease GERD ; a serious heart condition or active bleeding; glaucoma; myasthenia gravis; or if you are breast-feeding a baby. Absorption and Distribution In man, dicyclomine is rapidly absorbed after oral administration, reaching peak values within minutes. Your doctor may occasionally change your dose to make sure you get the best results. If a dose is missed, patients should continue the normal dosing schedule 2. Long-term animal studies have not been conducted to evaluate the carcinogenic potential of dicyclomine.
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