Sitagliptin maximum dose per day

Januvia sitagliptin is a prescription brand-name medication, sitagliptin maximum dose per day. The Food and Drug Administration FDA has approved it to treat type 2 diabetes in adults, in combination with exercise and a balanced diet. Januvia is available as a generic medication called sitagliptin. Sitagliptin is the active drug in Januvia.

Objective: In clinical trials, the degree of glucose lowering with sitagliptin has been correlated with the magnitude of dipeptidyl peptidase-4 DPP-4 inhibition over 24 h. However, sitagliptin mg once daily provided numerically greater percent plasma DPP-4 inhibition compared with mg once daily. The purpose of this study was to evaluate whether sitagliptin mg once daily provides greater improvement in glycemic efficacy as assessed by weighted mean glucose WMG over 24 h relative to sitagliptin mg once daily and to relate the percent DPP-4 inhibition achieved with these doses to any between-treatment differences in glycemic efficacy. Each of the treatment periods was 7 days in duration, with day washout periods between treatments. After each treatment period, patients underwent blood sampling at various time points over 24 h to determine h WMG. Plasma DPP-4 activity was assessed at trough, 24 h following dosing on day 7; percent DPP-4 inhibition was corrected for sample assay dilution. Following a planned interim analysis, the study was stopped because the h WMG values were not different between the sitagliptin doses.

Sitagliptin maximum dose per day

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Metformin and sitagliptin combination should be taken with meals to help reduce any stomach upset. Take the extended-release tablets as directed in the evening. Swallow the extended-release tablet or immediate-release tablet whole. Do not crush, break, or chew it. Carefully follow the special meal plan your doctor gave you.

If you miss a dose of this medicine, take it as soon as possible.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Back to Sitagliptin. Your doctor might prescribe a lower dose of 25mg or 50mg a day if you have problems with your kidneys. Take sitagliptin once a day. You can take it at any time, for example, in the morning or in the evening. But try to take it at the same time every day. Take your tablet with a drink of water. Swallow the tablet whole, without breaking it. Sitagliptin helps keep your blood sugar level as normal as possible to prevent health problems. You'll probably have to take it for a long time, even for the rest of your life.

Sitagliptin maximum dose per day

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Carefully follow the special meal plan your doctor gave you.

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Ask your doctor if you have any questions. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Take this medicine exactly as directed by your doctor. Exercise regularly and test for sugar in your blood or urine as directed. Contact Us. This content does not have an Arabic version. News Network. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. They may be taken with or without food, and at any time of day. Metformin and sitagliptin combination should be taken with meals to help reduce any stomach upset.

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Another option is to call the American Association of Poison Control Centers at or use its online tool. Help us advance cardiovascular medicine. They may be taken with or without food, and at any time of day. News Network. Exercise regularly and test for sugar in your blood or urine as directed. Swallow the tablet whole, without breaking it. Talk to your doctor if you take more than your prescribed dose of sitagliptin and:. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Degree Programs. To do so may increase the chance of side effects. Drugs and Supplements Sitagliptin Oral Route. Products and services. Levemir dosage. This content does not have an Arabic version. International Business Collaborations.