Tigecycline tablets

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Tigecycline injection is used to treat bacterial infections in many different parts of the body eg, infections on the skin, stomach, or lungs. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. This is a tetracycline antibiotic. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make.

Tigecycline tablets

Tigecycline , sold under the brand name Tygacil , is a tetracycline antibiotic medication for a number of bacterial infections. It was developed in response to the growing rate of antibiotic resistant bacteria such as Staphylococcus aureus , Acinetobacter baumannii , and E. It was given a U. Tigecycline is used to treat different kinds of bacterial infections, including complicated skin and structure infections, complicated intra-abdominal infections and community-acquired bacterial pneumonia. Tigecycline is given intravenously and has activity against a variety of Gram-positive and Gram-negative bacterial pathogens, many of which are resistant to existing antibiotics. Tigecycline successfully completed phase III trials in which it was at least equal to intravenous vancomycin and aztreonam to treat complicated skin and skin structure infections , and to intravenous imipenem and cilastatian to treat complicated intra-abdominal infections. It has no activity against Pseudomonas spp. The drug is licensed for the treatment of skin and soft tissue infections as well as intra-abdominal infections. Most C. Tigecycline can also be used in vulnerable populations such as immunocompromised patients or patients with cancer.

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Tigecycline adalah obat untuk menangani infeksi bakteri pada organ di dalam perut intraabdomen , infeksi kulit yang berat, atau pneumonia. Obat ini tersedia dalam bentuk suntik yang hanya bisa diberikan oleh dokter atau petugas medis di bawah pengawasan dokter. Tigecycline bekerja dengan cara menghambat pembentukan protein yang penting untuk pertumbuhan dan perkembangan bakteri. Perlu diingat bahwa obat ini hanya digunakan untuk mengobati infeksi bakteri , tidak bisa digunakan untuk mengatasi infeksi virus. Tigecycline belum diketahui dapat terserap ke dalam ASI atau tidak. Bila Anda sedang menyusui, jangan menggunakan obat ini tanpa berkonsultasi dulu dengan dokter.

Tigecycline tablets

Medindia » Drugs » Tigecycline. Follow MedIndia. Tigecycline Price of 6 Brands. The Price section compares costs of the same generic drugs across brands and is purely for information purpose.

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Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Diagn Microbiol Infect Dis. It has no activity against Pseudomonas spp. Use a sunscreen when you are outdoors. This includes prescription or nonprescription over-the-counter [OTC] medicines and herbal or vitamin supplements. For MRSA and other resistant organisms, vancomycin remains the least expensive and daptomycin the most expensive agent. A study evaluated the pharmacokinetics of tigecycline in patients with mild, moderate, and severe hepatic impairment Child-Pugh class A, B, and C, respectively 1. One study evaluated the pharmacodynamic activity of tigecycline against Streptococcus pneumoniae, Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae using the neutropenic murine thigh model. Safety and efficacy have not been established. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Cancer Cell. It should not be used for patients who are not at risk of resistant infections or in patients who have infections sensitive to vancomycin, unless the patient is not responding to vancomycin therapy.

Tigecycline is an antibiotic that fights bacteria in the body. Tigecycline is used to treat many different bacterial infections of the skin or the digestive system, as well as pneumonia. Tigecycline should be used only for infections that cannot be treated with other medicines.

Diagn Microbiol Infect Dis. Most C. Treatment was continued for up to 14 days. Laboratory abnormalities probably related to tigecycline included elevated serum levels of transaminases, alkaline phosphatase, and blood urea nitrogen as well as anemia. Clindamycin Lincomycin Pirlimycin. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Gram-positive organisms continue to increase in resistance, and very few agents are available to treat these infections. Tigecycline may be more effective than other tetracyclines against anaerobic organisms such as Bacteroides fragilis, Peptostreptococcus species, and Propionibacterium acnes. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Concentrations of tigecycline in the gallbladder, lung, and colon are higher than serum concentrations 1 , while concentrations of tigecycline in the bone and synovial fluid are lower than serum concentrations 7. AcrAB efflux pump plays a role in decreased susceptibility to tigecycline in Morganella morganii. Two veterinary Salmonella strains resistant to earlier investigational glycylcyclines have been isolated, but no resistance to tigecycline was noted. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. S2CID